In my lab, we are interested in the development and healthy maintenance of blood vessels. Certain diseases require blood vessel development for their progression; tumors, for example, thrive on blood flow. In those situations, we want to know how to stop or reverse vessel growth in order to halt disease progression. At other times, such as when wounds are healing, vessel growth is necessary and positive. In those cases, we want to learn how to build new vessels.
Blood vessel development is similar in mice and humans, so we use mice to study and manipulate vessels. By altering one or two genes at a time in mice, we can begin to understand how those genes contribute to blood vessel development and maintenance. We ultimately hope to identify genes that are critical for building and protecting healthy blood vessels, since those genes would be important therapeutic targets for controlling the growth and upkeep of blood vessels in our bodies.
Publications
Founded in 1946, the Oklahoma Medical Research Foundation (OMRF) is among the nation’s oldest, most respected independent, nonprofit biomedical research institutes. OMRF is dedicated to understanding and developing more effective treatments for human diseases, focusing on critical research areas such as Alzheimer’s disease, cancer, lupus, Multiple Sclerosis, and cardiovascular disease. OMRF follows an innovative cross-disciplinary approach to medical research and ranks among the nation’s leaders in patents per scientist.
Located in Oklahoma City, a city that offers a dynamic and flourishing downtown area, with low cost of living, short commute times and a diversified economy, OMRF has been voted one of the Top Workplaces since the inception of the award. This achievement has been accomplished thanks to OMRF individuals who share a unified understanding that our excellence can only be fully realized with a commitment to diversity, equity, and inclusion. Successful candidates will demonstrate commitment to these values
We offer competitive salaries and comprehensive benefits including, medical, dental, and vision insurance, minimum 8% company retirement contribution, vacation and sick leave, paid holidays, onsite café, free onsite fitness center with access to personal trainer, free parking and much more! Relocation assistance available for those located 50 miles outside of Oklahoma City metro and out of state. Learn more about our benefits here.
OMRF is an Equal Opportunity/Affirmative Action/Veterans Employer. All qualified applicants will receive consideration for employment without regard to gender, sexual orientation, gender identity, race, color, national origin, age, religion, disability, veteran status, or any other legally protected characteristic
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