The Immunogenetics of Lupus

The Nath laboratory in the Arthritis and Clinical Immunology research program is seeking a highly motivated, self-starter staff-scientist/post-doctoral level with the ability to work with optimal resources and little direct supervision to address important questions in the genetics and genomics of the systemic lupus erythematosus, an autoimmune diseases.

We will apply various modern techniques for studying features of three-dimensional (3D) genomic organization such as 3C, Hi-C, ChIP-Seq, RNA-seq and genome editing using CRISPR/Cas9 based techniques. Successful candidate will be proficient in a wide range of analytical methods and the use of bioinformatics/genetics software for analyzing and interpreting various types of data.

Successful candidates will be proficient in wide range of contemporary molecular biology techniques such as, high-throughput sequencing of DNA, RNA, and methylation, ChIP-Seq, ChIP-qPCR, Single cell genomics, flow cytometry, cloning, cell culture etc. Experience in genome CRISPR/Cas9 or similar approaches will get preference. Competitive individuals will also have some experience in the analysis of genetic data, high-throughput sequencing data and the use of bioinformatics software.