James Lab
Research job openings
About the Lab:
Our research is unified by a single goal: To improve the lives of patients with systemic autoimmune diseases by providing knowledge and tools for earlier, more precise treatment.
Systemic lupus erythematosus (SLE) is a leading cause of death among women between 5 and 64 years of age in the US. By the time patients reach SLE classification, the majority exhibit organ/tissue damage and ongoing, aggressive inflammatory processes. This damage is compounded by toxicities from long-term treatment with steroids and potent immunosuppressants. Earlier initiation of effective treatment would reduce these risks, but requires accurate tools for diagnosis, prognosis, and treatment selection.
To delineate the immune pathways that lead to SLE onset and disease flares, and to define their potential as biomarkers, we survey the immune alterations at various stages of disease in an unparalleled collection of clinical data and patient samples. Our group uses a combination of cutting edge proteomics, transcriptomics, single cell analyses, immune phenotyping, and mathematical modeling to identify signatures that associate with a patient’s clinical progression and treatment responses. These signatures are a critical step toward personalized medicine for lupus patients.
Lab perks and benefits:
Founded in 1946, the Oklahoma Medical Research Foundation (OMRF) is among the nation’s oldest, most respected independent, nonprofit biomedical research institutes. OMRF is dedicated to understanding and developing more effective treatments for human diseases, focusing on critical research areas such as Alzheimer’s disease, cancer, lupus, Multiple Sclerosis, and cardiovascular disease. OMRF follows an innovative cross-disciplinary approach to medical research and ranks among the nation’s leaders in patents per scientist.
Located in Oklahoma City, a city that offers a dynamic and flourishing downtown area, with low cost of living, short commute times and a diversified economy, OMRF has been voted one of the Top Workplaces since the inception of the award. This achievement has been accomplished thanks to OMRF individuals who share a unified understanding that our excellence can only be fully realized with a commitment to diversity, equity, and inclusion. Successful candidates will demonstrate commitment to these values
We offer competitive salaries and comprehensive benefits including, medical, dental, and vision insurance, minimum 8% company retirement contribution, vacation and sick leave, paid holidays, onsite café, free onsite fitness center with access to personal trainer, free parking and much more! Relocation assistance available for those located 50 miles outside of Oklahoma City metro and out of state. Learn more about our benefits here.
OMRF is an Equal Opportunity/Affirmative Action/Veterans Employer. All qualified applicants will receive consideration for employment without regard to gender, sexual orientation, gender identity, race, color, national origin, age, religion, disability, veteran status, or any other legally protected characteristic
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